Carte "Vintage ad-1854-Nichols Peruvian Bark & Iron

Mise à l'heure actuelle, from 1854 ad by distributer : "BILLIONS CLAPP & CO BOSTON" (Mis-spelling and all) "AN OLD AND VALUABLE REMEDY Nichols Elixir of Peruvian Barl With Protoxide of Iron A prominentarpecarent ity and advplantation consis ts in associating Iron not geaquioxide condition but in the more easily assimilable forme of a protoealti with the valuable alkaloids of Peruvian Bark in elegant and permanent conipo where the chemical equilibrium of each is unprincipal urbed We unhesitgly express that no more pleasant and desirable chalybeate and tonic has ever been ottered to the profession and so far as our knowledge extends this result the combination of the protosaltti of Iron with the active principles of Peruvian Bark is not attained in any of the numerous preparations crowded upon the public a j tltute and imitation of our compound in order that physicians may prove the presence of protoxide of iron in this Elixir we rive the oral teet Pour a small quantity of the Elixir into a wine glass and add a few drops of ferricyanide of potef aium the instantanchange of color a deep blue snows the presence of iron in the form of a protoiaU Our Elixir of Peruvian Barr with Protoxide of Iron is bottles holding one pint donc two two quart and gallon paokage If cians desiring to bulbe this préparation veut their drugts to procger the larger tles they can order it by pieacripticn in suoh quantities as the may desire for their patients Made only by BILLIONS CLAPP & CO BOSTON " Modern info- Quinine is the chief alkaloid of cinchona bark (known 'fever bark'), a tree foet in South America. It has a colourful history of more than 350 ans. Calancha, à Augustinian monk of Lima, first wred about the curative properties of cinchona powder in fevers and tertians as early as en 1633. By 1640, the bark had already found its way into Europe, thanks to the Jesuit fathers (hence the name 'Jesuit's bark') Cardinal de Lugo popularised the bark in Rome (hence it is called cardinal's bark). En 1820, Pelletier et Caventou isolated quinine et cinchonine from cinchona. Even today, quinine is obtained entirely from the natural sources due the difficulté in synthesising the complex molecule.